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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCYL3
All Species:
18.18
Human Site:
S389
Identified Species:
33.33
UniProt:
Q8IZE3
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8IZE3
NP_065156.5
742
82857
S389
L
L
G
L
R
D
T
S
D
S
I
V
A
I
T
Chimpanzee
Pan troglodytes
XP_513987
742
82925
S389
L
L
G
L
R
D
T
S
D
S
I
V
A
I
T
Rhesus Macaque
Macaca mulatta
XP_001096051
736
82375
S389
L
L
G
L
R
D
T
S
D
S
I
V
A
I
T
Dog
Lupus familis
XP_537198
743
82483
S389
L
L
G
L
R
D
T
S
D
S
I
V
A
I
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBQ7
735
81315
S389
L
L
G
L
R
D
T
S
N
S
I
V
A
I
T
Rat
Rattus norvegicus
Q5M9F8
807
89107
N423
A
P
K
L
S
E
T
N
L
N
V
E
L
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514536
1518
163635
N1014
L
L
G
L
R
D
T
N
D
S
I
V
A
I
T
Chicken
Gallus gallus
NP_001012613
698
77220
E369
P
E
V
V
V
G
G
E
R
T
K
I
F
K
S
Frog
Xenopus laevis
Q561M0
827
91284
A480
D
P
F
A
P
S
R
A
A
G
V
L
G
F
A
Zebra Danio
Brachydanio rerio
NP_955951
768
85305
N390
L
L
G
M
R
D
T
N
D
S
L
V
A
M
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610175
683
77833
L356
L
R
D
A
Q
I
R
L
I
L
L
D
Y
F
M
Honey Bee
Apis mellifera
XP_001123124
613
70111
P287
I
K
K
L
K
I
F
P
E
N
I
I
A
E
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001177952
810
89574
H401
L
L
G
L
K
D
H
H
T
N
L
V
A
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
95.1
85.5
N.A.
80.7
21.9
N.A.
31.8
61.9
21.8
51.9
N.A.
25.7
28.4
N.A.
33.5
Protein Similarity:
100
99.1
96.7
90.3
N.A.
87.7
38.5
N.A.
37.4
71.5
39
67.5
N.A.
45.9
49.7
N.A.
50.7
P-Site Identity:
100
100
100
100
N.A.
93.3
13.3
N.A.
93.3
0
0
73.3
N.A.
6.6
20
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
100
46.6
N.A.
100
26.6
20
100
N.A.
20
53.3
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
16
0
0
0
8
8
0
0
0
70
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
8
0
0
62
0
0
47
0
0
8
0
8
0
% D
% Glu:
0
8
0
0
0
8
0
8
8
0
0
8
0
8
0
% E
% Phe:
0
0
8
0
0
0
8
0
0
0
0
0
8
16
0
% F
% Gly:
0
0
62
0
0
8
8
0
0
8
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
8
8
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
0
0
16
0
0
8
0
54
16
0
47
0
% I
% Lys:
0
8
16
0
16
0
0
0
0
0
8
0
0
8
8
% K
% Leu:
70
62
0
70
0
0
0
8
8
8
24
8
8
8
0
% L
% Met:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
8
% M
% Asn:
0
0
0
0
0
0
0
24
8
24
0
0
0
0
0
% N
% Pro:
8
16
0
0
8
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
8
0
0
54
0
16
0
8
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
8
8
0
39
0
54
0
0
0
0
16
% S
% Thr:
0
0
0
0
0
0
62
0
8
8
0
0
0
0
54
% T
% Val:
0
0
8
8
8
0
0
0
0
0
16
62
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _